OPEN-ACCESS PEER-REVIEWED

1Manju, 2Manvy Chalana, 3Sandeep Kumar, 4Ashwini Manhas, 5Kawal Preet Kaur, 6Shwaita Goyal, 7*Priyanka

1Assistant Professor, Department of Microbiology, Adesh Medical College & Hospital-Shahbad, Haryana 2Assistant Professor, Department of Microbiology, Adesh Medical College & Hospital-Shahbad, Haryana 3Assistant Professor, Department of Biochemistry, World College of Medical Sciences, Jhajjar Haryana 4Professor & Head, Department of Microbiology, Adesh Medical College & Hospital-Shahbad, Haryana

5Ex-Professor, Department of Microbiology   Maharaja Agrsen Medical College & Hospital, Agroha, Hisar

6EX-Assistant Professor, MMU, Solan

7Senior-Resident, Department of Microbiology AIIMS, Bathinda India

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Abstract

Background: The prevalence of urinary tract infections in diabetic women is higher than in men. Urinary tract infections make it difficult to control blood sugar in diabetic patients, which increases the need for blood sugar monitoring, reduces the quality of life, and imposes significant treatment costs on the patient. Hence; the present study was conducted for analyzing microbiological profile and antibiotic sensitivity pattern among diabetic patients with UTI.
Materials & methods: A total of 100 patients with presence of type 2 diabetes mellitus were enrolled. Complete demographic and clinical details of all the patients was obtained. The presence of bacteria was considered diagnostic indicators for urinary tract infections. The pathogen was identified using urine culture investigation, which was limited to individuals whose urine microscopy revealed infection. All the results were recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software.
Results: UTI was seen in 30 percent of the patients. Escherichia coli was the predominant micro-organism found to be present in 56.67 percent of the patients. Klebsiella species, Enterobacter species, Staphylococcus species and Pseudomonas aeruginosa was present in
13.33 percent, 13.33 percent, 10 percent and 6.67 percent of the patients respectively. E.coli was mainly susceptible to Cefotaxime, Cefuroxime, Amikacin, ciprofloxacin and meropenem. Similar pattern was recorded for Klebsiella and Enterobacter. Staphylococcus species was susceptible to cefotaxime, ciprofloxacin and Nalidixic acid. Pseudomonas species was susceptible to Cefuroxime.
Conclusion: UTI is found to be affecting significant proportion of type 2 diabetic patients. Hence; adequate knowledge of the microbiological profile and antibiotic sensitivity patterns helps early treatment planning and reducing the morbidity associated with it.

Keywords: Microbiological Profile, Antibiotic sensitivity, Diabetic

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