OPEN-ACCESS PEER-REVIEWED
1*Ms. Puja Saha, 2Dr. Sumit Kumar Sar, 3Karthik H P, 4Chandan Kumar Mohapatra, 5Dr Swastika Tiwari, 6Selvaraj Sudhakar
1*Nursing Tutor, Institute of Nursing, Brainware University, Barasat, West Bengal State – West Bengal
2Assistant Professor, Department of Computer Science and Engineering, Bhilai Institute of Technology
Durg, Chhattisgarh, India.
3Assistant Professor, Agricultural Economics, School of Agriculture, S R University, 506371, Warangal Telangana, India.
4Faculty Associate School of sports and Yogic sciences, KIIT UNIVERSITY, Bhubaneswar, Odisha
5Shaheed Rajguru college of applied Sciences, Delhi university
6Professor, Faculty of Physiotherapy, Dr.M.G.R. Educational and Research Institute, Maduravoyal, Chennai – 600095, Tamil Nadu, India.
Abstract
This research aimed to isolate and determine the amount of naringin in different grapefruit types, assess the effectiveness of different solvents in extraction and investigate the therapeutic value of naringin. Ruby Red, Star Ruby, White, and yellow grapefruits were used in this experiment and the grapefruits were extracted using ethanol before the naringin content was determined using HPLC. Comparison was made between extraction yields using ethanol, methanol, acetone, and hexane. The content of naringin in extracts was measured, and its therapeutic effects were described. The concentration of naringin also differed with the type of grapefruit; Ruby Red contained the highest amount of naringin (15. 2 mg/g) followed by Star Ruby (12. 5 mg/g). It was found that ethanol was the best solvent yielding 8. 9% of the product. The concentration of naringin was highest in the yellow grapefruit extracts at 28. 5 mg/mL. Some of the pharmacological properties of naringin are anti-inflammatory, cardio-protective and anticancer activity. The results have shown that the choice of grapefruit variety and solvent has a great effect on the yield of naringin extraction. Ruby Red and Yellow grapefruits are the richest sources of naringin. Due to the versatility of the therapeutic effects of naringin, there is a need for further research and possibly the inclusion of naringin in clinical practice.
Keywords: Naringin, grapefruit varieties, solvent extraction, HPLC, bioactive compounds.
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