OPEN-ACCESS PEER-REVIEWED
1K. Senthilkumar, 2A. Vijayalakshmi
Ph. D Scholar, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Pallavaram, Chennai 600 117, Tamilnadu, India.
2Professor, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Pallavaram, Chennai 600 117, Tamilnadu, India
Abstract
Background/Objectives:
UV radiation causes sunburn and prolonged exposure signs. Sunscreens protect by absorbing, reflecting, and scattering UV rays. Advancements include non-traditional UV filters and botanical compounds. Effective sun protection is crucial. Microbiological protection is essential in cosmetics to prevent damage and infections. This study aimed to identify self-preserving preservative complexes for sun care products, comparing their efficacy to conventional preservatives.
Methods:
MICs of cosmetic ingredients were assessed to identify antimicrobial compounds. Synergy indices were determined using combinations of multifunctional components. Formulations for self-preserving sun care products were evaluated using Preservative Challenge Testing.
Results:
Synergistic combinations, e.g., Sodium grapeseedamidopropyl PG-dimonium chloride phosphate: inulin: tetrasodium glutamate diacetate (ratios 0.65:12.5:25, 0.5:12.5:30, and 1:12.5:30), effectively minimized microbiological challenges, comparable to traditional preservatives.
Conclusions:
This study shows self-preserving sun care solutions can be developed by selecting multifunctional components. These products maintain aesthetics, sensory attributes, and resist microbial attacks like traditional preservatives. Exploring multifunctional components offers a potent alternative, promoting cosmetic-friendly preservation while mitigating risks.
Keywords: Antimicrobial, self-preservation, sun care formulations, conventional preservatives, multifunctional ingredients.
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