OPEN-ACCESS PEER-REVIEWED ORIGINAL RESEARCH Yulia Benitex1, Jonathan Davis2, David L. Wensel3, Tracy S. Mitchell4, Mark R. Krystal5, Dieter M. Drexler1,* 1Bristol Myers Squibb Company, Research & Development, Pharmaceutical Candidate Optimization,…
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OPEN-ACCESS PEER-REVIEWED REVIEW ARTICLE Catherine E. DelGuidice1,2, Omnia A. Ismaiel2,3, William R. Mylott Jr2, Matthew S. Halquist1,* 1Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, USA. 2PPD…
Read MoreAddressing Bioanalytical Needs of Antibody-Based Biotherapeutics by LC-MS
OPEN-ACCESS PEER-REVIEWED FOREWORD Morse Faria PPD Laboratories, Richmond, VA 23230, USA. Journal of Applied Bioanalysis. Vol.6. No.1. pages 7-11 (2020) Published 15 January 2020. https://doi.org/10.17145/jab.20.003 | (ISSN 2405-710X) Download PDF…
Read MoreMaking a Difference in Therapeutic Drug Monitoring of Antimicrobial Drugs; the Need for LC-MS/MS
OPEN-ACCESS PEER-REVIEWED EDITORIAL Jan-Willem C. Alffenaar and Daan J. Touw University of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands. Journal of Applied Bioanalysis.…
Read MoreCurrent Status of Anti-Drug Antibody Analysis Using Immunocapture-Liquid Chromatography/Mass Spectrometry
OPEN-ACCESS PEER-REVIEWED REVIEW ARTICLE Linzhi Chen Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT 06877, USA. Journal of Applied Bioanalysis. Vol.4. No.3. pages 70-84 (2018) Published 15 July 2018.…
Read MoreA validated high-resolution accurate mass LC-MS assay for quantitative determination of metoprolol and alpha-hydroxymetoprolol in human serum for application in pharmacokinetics
OPEN-ACCESS PEER-REVIEWED RESEARCH ARTICLE Sjoukje Postma-Kunnen1,†, Jan Peter Yska1,†,*, Gerard Hommema1, Sikke Koopmans1, Bob Wilffert2,3, Eric N. van Roon1,2 1Department of Clinical Pharmacy and Clinical Pharmacology, Medical Centre Leeuwarden, Leeuwarden, the…
Read MoreLC-MS multi-attribute method for characterization of biologics
OPEN-ACCESS PEER-REVIEWED EXPERT OPINION Xiaobin Xu*, Haibo Qiu, Ning Li Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA. Journal of Applied Bioanalysis. Vol.3. No.2. pages 21-25 (2017) Published…
Read MoreCan LC and LC-MS ever replace immunoassays?
OPEN-ACCESS PEER-REVIEWED EXPERT OPINION Timothy G. Cross* and Martin P. Hornshaw Thermo Fisher Scientific, Hemel Hempstead, Hertfordshire, United Kingdom. Journal of Applied Bioanalysis. Vol.2. No.4. pages 108-116 (2016) Published 15…
Read MoreA generic sample preparation approach for LC–MS/MS bioanalysis of therapeutic monoclonal antibodies in serum applied to Infliximab
OPEN-ACCESS PEER-REVIEWED RESEARCH ARTICLE Anne J. Kleinnijenhuis*, Jan H. Toersche, Frédérique L. van Holthoon, Richard C. Bas, William D. van Dongen† Journal of Applied Bioanalysis. Vol.1. No.1. pages 26-34 (2015) Published…
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